WebCryptotanshinone is a potent anticancer agent targeting the activation STAT3 protein with antitumor activity. Buy STAT inhibitor Cryptotanshinone (CTS) from AbMole BioScience. … WebCryptotanshinone (CTS), a major constituent from the roots of Salvia miltiorrhiza (Danshen), is widely used in the treatment of coronary heart disease, stroke and less commonly Alzheimers disease. Our recent study indicates that CTS is a substrate for Pglycoprotein (PgP/MDR1/ABCB1).
Cryptotanshinone specifically suppresses NLRP3 inflammasome …
WebResearch progress of cryptotanshinone on anti-fibrosis and its mechanism LIU Yayi1, ZHANG Junping1,2(1. School of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China; ... cryptotanshinone (CTS) has a good anti-fibrosis effect in various organs and tissues. However, its mechanism of action has not been clearly ... WebFeb 8, 2024 · Here, we propose a potential combination for HCC treatment named arsenic trioxide cooperate cryptotanshinone (ACCS). A remarkable synergistic therapeutic effect has been achieved compared with drugs alone in both in vivo and in vitro experiments. reach climbing philadelphia
Frontiers Uncovering the Mechanisms of Cryptotanshinone as a ...
WebAug 13, 2024 · Cryptotanshinone (CPT), an active compound isolated from Radix Salviae Miltiorrhizae, has been reported to possess diverse pharmacological activities, including … WebFeb 1, 2024 · Cryptotanshinone (CTS) is a specific inhibitor for NLRP3 inflammasome. • CTS blocks Ca 2+ signaling and the induction of mtROS, the important upstream signalings of NLRP3 inflammasome activation. • CTS exhibits protective effect in inflammasome-mediated diseases such as endotoxemia syndrome and MCD-diet-induced NASH. Abstract WebOct 26, 2024 · Cryptotanshinone could induce the transition of M1 subtype to M2 subtype as indicated by up-regulated expression of arginase 1 (ARG1), interleukin (IL)-10, and CD206. In vivo, orally administrated NP CTS accumulated in … how to spot fleas on a dog