Cthrc1 kda

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August undefined, 2024

WebProteolytic processing may generate multiple CTHRC1 isoforms. There is the potential for an intracellular full-length 33 kDa, 245 aa form, plus extracellular isoforms that are 28 kDa (aa 33-245), 26 kDa (aa 49-245), 20 kDa (aa 98‑245) and 18 kDa and 16 kDa in size, the last two representing variants of the 20 kDa form with C-terminal processing. WebApr 15, 2002 · Hepatocellular carcinoma (HCC) Malignant behaviors microRNA-155-5p (miR-155-5p) Collagen triple helix repeat containing 1 (CTHRC1) GSK-3β-involved Wnt/β-catenin signaling; ... Osteosarcoma microRNA-338-3p Activator of 90 kDa heat shock protein ATPase homolog 1 Tumor suppressor Translational repression; 82.

The Role of CTHRC1 in Regulation of Multiple Signaling and

WebMay 13, 2024 · CTHRC1 is highly expressed in patients with primary CRC and hepatic metastasis of CRC and predicts a poor prognosis. To … Web~Two bands of 25-30 kDa (SDS-PAGE) Purity: ≥90% (SDS-PAGE) Endotoxin Content: 0.01EU/μg purified protein (LAL test). Concentration: 0.1mg/ml after reconstitution. ... Collagen triple helix repeat containing-1 (CTHRC1) is a 30kDa glycosylated secretory protein containing a short collagen-like motif contributing to vascular remodeling by ... dynamic reverse bias drb

The Role of CTHRC1 in Regulation of Multiple Signaling …

WebCTHRC1 was immunoprecipitated from 0.35 mg SK-MEL-28 (Human malignant melanoma) whole cell lysate with ab256458 at 1/30 dilution (2ug in 0.35mg lysates). Western blot was performed on the immunoprecipitate using ab256458 at 1/1000 dilution. VeriBlot for IP Detection Reagent (HRP) was used at 1/5000 dilution. WebFeb 9, 2012 · Collagen Triple Helix Repeat Containing-1 (CTHRC1) and Nuclear factor (erythroid-derived 2)-like 3 ... expression level in colorectal tumours when compared with normal tissues [9-12]. CTHRC1 is a 30 kDa secreted protein that has the ability to inhibit collagen matrix synthesis. WebMay 13, 2024 · CTHRC1 is highly expressed in patients with primary CRC and hepatic metastasis of CRC and predicts a poor prognosis. To identify the potential metastasis-associated genes in primary CRC, we first ... dynamic rgb pc speakers

RT-PCR with Cthrc1 specific primer pair was performed on

CTHRC1 Antibody (1G12) (H00115908-M05): Novus Biologicals

WebOct 11, 2024 · Collagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein reported to be involved in vascular remodeling, bone formation and morphogenesis. This study aimed to investigate the role of CTHRC1 in promoting the metastasis of EOC and to elucidate the underlying molecular mechanisms. WebThe recombinant human CTHRC1 consists of 224 amino acids and has a predicted molecular mass of 24.5 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CTHRC1 is approximately … dynamic rheological experimentsWebThe molecular weight of secreted CTHRC1 (30 kDa) appears to be larger than that of cellular CTHRC1 (26 kDa). CTHRC1 has four different isoforms with molecular weights of about 12.3 kDa to 27 kDa ... dynamic riders

"WebFeb 9, 2012 · Collagen Triple Helix Repeat Containing-1 (CTHRC1) and Nuclear factor (erythroid-derived 2)-like 3 (NFE2L3) may be useful biomarker candidates for the diagnosis of colorectal cancer (CRC) since they have shown an increase messenger RNA transcripts (mRNA) expression level in adenomas and colorectal tumours when compared to normal … " - Cthrc1 kda

Cthrc1 kda

Collagen triple helix repeat containing 1 (CTHRC1) activates …

WebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. ... Highly conserved from lower chordates to mammals, the CTHRC1 protein was identified as a 30 kDa secreted protein and was first verified to be a differentially expressed gene in balloon-injured rat … WebCthrc1 is a 30 kDa secreted protein that has the ability to inhibit collagen matrix synthesis. Cthrc1 is also glycosylated and retains a signal sequence … We recently identified collagen triple helix repeat containing-1 (Cthrc1) as a novel gene induced in adventitial fibroblasts after arterial injury.

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WebCTHRC1 (Collagen triple helix repeat-containing protein 1) is a 28-30 kDa, secreted glycoprotein that bears similarity to the C1q/TNF alpha -related family of proteins. It is expressed by disparate cell types, including renal epithelium, neurons, osteoblasts, and smooth muscle cells. WebFor the independent antibodies validation the evaluation is based on comparison of the staining of two (or more) independent antibodies directed towards independent epitopes on the protein. For all cases except the siRNA validation, an image representative of the antibody staining pattern is shown.

WebImmunohistochemistry-Paraffin: CTHRC1 Antibody [NBP2-31797] - Staining of human pancreas shows low positivity in glandular cells as expected. Immunohistochemistry-Paraffin: CTHRC1 Antibody [NBP2-31797] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. WebOct 6, 2024 · Collagen triple helix repeat containing 1 (CTHRC1), a 30 kDa protein is generally expressed in developing bones, cartilage, and myofibroblasts during wound healing 5.

WebCollagen triple helix repeat containing protein 1 (CTHRC1) is a 30 kDa secreted glycoprotein encoded by the CTHRC1 gene. CTHRC1 is known to regulate extracellular collagen deposition and partake in vascular remodeling of arterial injury as a function of cellular response through the TGF-β and Wnt pathways. Moreover, WebCTHRC1 protein expression summary. Single band larger than predicted size in kDa (+20%) but partly supported by experimental and/or bioinformatic data.

WebCTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. dynamic reviewWebCTHRC1 (Collagen triple helix repeat-containing protein 1) is a 28-30 kDa, secreted glycoprotein that bears similarity to the C1q/TNF alpha -related family of proteins. It is expressed by disparate cell types, … dynamic riders hyderabadWebCTHRC1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells, in the hypothalamus, pituitary gland and remodeling tissues. Aberrant expression of CTHRC1 is present in human solid cancers and likely to be associated with … dynamic rhytidesWebApr 17, 2024 · CTHRC1 has four different isoforms with molecular weights of about 12.3 kDa to 27 kDa; the full-length of CTHRC1 accounts for both secreted and cellular CTHRC1 . Glycosylated protein CTHRC1 with a … dynamic rhetoricWeb25.3 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. ... There are no reviews for CTHRC1 Recombinant Protein (NBP2-52008). By submitting a review you will ... dynamic resurfacing pads elemisWebAll lanes : Anti-CTHRC1 antibody (ab264410) at 1/1000 dilution Lane 1 : UACC-62 whole cell lysate Lane 2 : MALME-3M whole cell lysate Lane 3 : SR whole cell lysate Lane 4 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate Lysates/proteins at 50 µg per lane. Developed using the ECL technique. Predicted band … dynamic rheometerWebCTHRC1 is a secreted glycoprotein with 12 repeats of the Gly-X-Y motif (a.a. 58-93 based on the pro-form seqeunce) that is reported to increase cell motility and promote cell migration by limiting the deposition of collagen matrix. dynamic rides hockley heath